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Tective protein hemeoxygenase-1 (HO-1).54 HO-1 is definitely the inducible, rate-limiting enzyme that degrades prooxidative and cytotoxic heme to bilirubin and carbon monoxide, every single of which has welldocumented antioxidant and antiinflammatory effects.54, 457?60 We showed that HIVinfection of MDM in vitro drastically decreases HO-1 protein expression and that induction of HO-1 in HIV-MDM lo

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